Journal
JOURNAL OF PEDIATRIC AND ADOLESCENT GYNECOLOGY
Volume 21, Issue 6, Pages 305-310Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/j.jpag.2007.09.006
Keywords
Vaginal agenesis; Testicular feminization; Hormone therapy; Genetic disorder; Vaginal dilatation
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This review paper highlights important diagnostic and therapeutic concerns for girls with Complete Androgen Insensitivity Syndrome (CAIS). CAIS is an androgen receptor defect disorder associated with vaginal and uterine agenesis in women with a 46,XY karyotype. The major clinical issues surrounding this syndrome include timing of gonadectomy, hormone replacement, vaginal dilation, and attention to psychological issues.
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