Journal
JOURNAL OF ORTHOPAEDIC TRAUMA
Volume 24, Issue 9, Pages 543-546Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/BOT.0b013e3181ec4833
Keywords
bone morphogenetic protein; gene therapy; VEGF; platelet rich plasma; PDGF; parathyroid hormone; fracture healing
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The current landscape of growth factors in orthopaedic trauma is dominated by the BMPs, as they ale the most extensively studied growth factors in clinical applications pertaining to orthopaedic trauma Despite this. their application and indications for use in trauma remain controversial This article highlights a number of selected growth factors, other than BMPs, that are currently being investigated in orthopaedic trauma applications These growth factors have shown significant promise in preclinical and early clinical investigation
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