Journal
JOURNAL OF ORTHOPAEDIC RESEARCH
Volume 30, Issue 8, Pages 1296-1303Publisher
WILEY
DOI: 10.1002/jor.22072
Keywords
microarc oxidation; osteoporosis; pedicle screw; interface; spinal fixation
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Funding
- National High Technology Research and Development Program of China (863 Program) [2007AA02Z468]
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Failure of fixation caused by loosening of pedicle screws in osteoporosis is a problem in spinal surgery. We compared the in vivo fixation strength between pedicle screws treated with microarc oxidation (MAO) and untreated screws in an osteoporotic model of ovariectomized sheep. The MAO treated and untreated screws were placed in lumbar vertebral bodies. After 3 months of implantation, biomechanical tests, micro-CT analysis, and histological observations were conducted to examine the performance of the two groups. At time 0, no significant difference was found between the two groups in biomechanical tests (p?>?0.05); 3 months later, higher pull-out strength and load with less displacement were detected in the MAO-treated group (p?
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