4.5 Article

Alkyne hydroamination triggered cyclizations: A powerful tool for the construction of biologically important structural motifs

Journal

JOURNAL OF ORGANOMETALLIC CHEMISTRY
Volume 696, Issue 1, Pages 419-432

Publisher

ELSEVIER SCIENCE SA
DOI: 10.1016/j.jorganchem.2010.10.027

Keywords

Metal catalyst; Hydroamination; Cyclization; Cascade reactions; Biologically important scaffolds

Funding

  1. Department of Science and Technology (DST), New Delhi
  2. Council of Scientific and Industrial Research (CSIR), India
  3. CSIR

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This review focuses mainly on recent endeavors in the field of cyclizations triggered by the catalytic hydroamination (formal or direct) of alkynes. The new strategies developed offer an efficient and convenient entry to several heterocycles of biological importance. (C) 2010 Elsevier B.V. All rights reserved.

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