Journal
JOURNAL OF ORGANOMETALLIC CHEMISTRY
Volume 694, Issue 21, Pages 3452-3455Publisher
ELSEVIER SCIENCE SA
DOI: 10.1016/j.jorganchem.2009.06.031
Keywords
alpha-Haloketone; alpha-Hydroxyketone; Cesium formate; Transformation
Categories
Ask authors/readers for more resources
A new safe and convenient transformation has been developed. In the presence of cesium formate in dry MeOH solution, alpha-haloketones underwent direct conversion reaction to afford alpha-hydroxyketone in excellent yields. Furthermore, this methodology can be extended and applied in 2-chloro-N-(1,3-diphenyl-1H-pyrazol-5-yl)acetamide, 2-chloro-N-(2,6-dimethylphen-yl)acetamide, 1-(bromomethylsulfonyl)benzene, and N-(bromomethyl)phthalimide to give the corresponding products in moderate to excellent yields. Crown Copyright (C) 2009 Published by Elsevier B.V. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available