4.5 Article

An eco-friendly procedure for the efficient synthesis of dialkyl α-aminophosphonates in aqueous media

Journal

JOURNAL OF ORGANOMETALLIC CHEMISTRY
Volume 693, Issue 21-22, Pages 3313-3317

Publisher

ELSEVIER SCIENCE SA
DOI: 10.1016/j.jorganchem.2008.07.037

Keywords

alpha-aminophosphonates; aldehydes; amines; aqueous media

Funding

  1. Birjand University Research Council
  2. Institute of Advanced Studies for Basic Sciences (IASBS)
  3. Shiraz University

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A new, convenient and high yielding procedure for the preparation of diethyl alpha-aminophosphonates in water by one-pot reaction of aldehydes, amines, tri/dialkyl phosphites in the presence of a low catalytic amount of [Cu(3,4-tmtppa)](MeSO(4))(4) (0.16 mol%) as a highly stable and re-usable catalyst is described. (C) 2008 Elsevier B.V. All rights reserved.

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