Journal
JOURNAL OF ORGANIC CHEMISTRY
Volume 83, Issue 19, Pages 12334-12356Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.joc.8b02068
Keywords
-
Categories
Funding
- ERC (European Research Council, Starting Grant iTools4MC) [iTools4MC, 334840]
- SNF [CRSII5_171026]
- EPFL
Ask authors/readers for more resources
Azides are building blocks of increasing importance in synthetic chemistry, chemical biology, and materials science. Azidobenziodoxolone (ABX, Zhdankin reagent) is a valuable azide source, but its safety profile has not been thoroughly established. Herein, we report a safety study of ABX, which shows its hazardous nature. We introduce two derivatives, tBu-ABX and ABZ (azidobenziodazolone), with a better safety profile, and use them in established photoredox- and metal-mediated azidations, and in a new ring-expansion of silylated cyclobutanols to give azidated cyclopentanones.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available