4.7 Article

A Visible-Light-Promoted Aerobic Metal-Free C-3 Thiocyanation of Indoles

Journal

JOURNAL OF ORGANIC CHEMISTRY
Volume 79, Issue 21, Pages 10588-10592

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/jo5015799

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Funding

  1. NSFC [21102097]
  2. Scientific Research Foundation for the Returned Overseas Chinese Scholars, State Education Ministry

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A simple and efficient visible-light-promoted method for the C-3 thiocyanation of indoles has been developed. The transformation uses Rose Bengal as the photocatalyst and air as the terminal oxidant. The reaction is mild, high-yielding, and environmentally benign.

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