4.7 Article

Preparation of 2,3-Dihydrofurans via a Double Allylic Substitution Reaction of Allylic Nitro Compounds

Journal

JOURNAL OF ORGANIC CHEMISTRY
Volume 79, Issue 17, Pages 8103-8109

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/jo5013042

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Funding

  1. Yamaguchi University

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A one-step conversion of allylic nitro compounds to substituted 2,3-dihydrofurans has been developed. Allylic nitro compounds, which are readily available from nitroalkenes and formaldehyde, underwent a double allylic substitution reaction catalyzed by a palladium complex to give 2,3-dihydrofurans in good yield.

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