Journal
JOURNAL OF ORGANIC CHEMISTRY
Volume 80, Issue 1, Pages 1-7Publisher
AMER CHEMICAL SOC
DOI: 10.1021/jo502408z
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Funding
- NIGMS NIH HHS [R01 GM087605] Funding Source: Medline
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Because of their greater stability and unique conformational properties, unnatural amino acids are highly valued by pharmaceutical, biological, and organic chemists. This synopsis surveys the various catalytic methods used to access enantioenriched, acyclic a,a-disubstituted a-amino acids with a focus on the processes developed since 2007, when the last major reviews in this area were published.
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