4.7 Article

Selective Synthesis of Polyfunctionalized Pyrido[2,3-b]indoles by Multicomponent Domino Reactions

Journal

JOURNAL OF ORGANIC CHEMISTRY
Volume 79, Issue 17, Pages 7935-7944

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/jo501049m

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Funding

  1. Natural Science Foundation of the Jiangsu Higher Education Institutions [10KJA150049, 11KJB150014]
  2. Natural Science Foundation of Jiangsu Province [BK20131160]
  3. Priority Academic Program Development of Jiangsu Higher Education Institutions
  4. Foundation of the Key Laboratory of Organic Synthesis of Jiangsu Province [JSK1210]

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A series of novel polyfunctionalized pyrido[2,3-b]indoles were synthesized by three- or four-component domino reactions under microwave irradiation. This protocol has the advantages of readily available starting materials, short reaction times, high yields, easy workup, and high chemo- and regioselectivities.

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