Journal
JOURNAL OF ORGANIC CHEMISTRY
Volume 79, Issue 19, Pages 9000-9008Publisher
AMER CHEMICAL SOC
DOI: 10.1021/jo501250u
Keywords
-
Categories
Funding
- National Natural Science Foundation of China [21202152]
- Zhejiang Provincial Natural Science Foundation [Y4110044]
Ask authors/readers for more resources
A straightforward assembly of 1,2-disubstituted indoles has been developed through a Cu(II)-catalyzed domino coupling/cyclization process. Under aerobic conditions, a wide range of 1,2-disubstituted indole derivatives were efficiently and facilely synthesized from 2-alkynylanilines and boronic acids. 2-(2-Bromoaryl)-1-aryl-1H-indoles, which were selectively generated in one pot under the Cu catalysis, afforded the indolo[1,2-f]phenanthridines via Pd-catalyzed intramolecular direct C(sp(2))-H arylation. The one-pot tandem approaches to the polycyclic indole derivatives were also successfully achieved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available