4.7 Article

Functionalization of Amides via Copper-Catalyzed Oxyalkylation of Vinylarenes and Decarboxylative Alkenylation of sp3 C-H

Journal

JOURNAL OF ORGANIC CHEMISTRY
Volume 79, Issue 15, Pages 7103-7111

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/jo501274f

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Funding

  1. Scientific Research Foundation for the Returned Overseas Chinese Scholars, State Education Ministry
  2. Priority Academic Program Development of Jiangsu Higher Education Institutions
  3. Project of Scientific and Technologic Infrastructure of Suzhou [SZS201207]
  4. Key Laboratory of Organic Synthesis of Jiangsu Province

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An efficient protocol was developed to prepare a series of derivatives from amides by copper-catalyzed oxyalkylation of vinylarenes and decarboxylative alkenylation of sp(3) C-H. This method is simple, practical, and inexpensive.

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