Journal
JOURNAL OF ORGANIC CHEMISTRY
Volume 79, Issue 10, Pages 4751-4756Publisher
AMER CHEMICAL SOC
DOI: 10.1021/jo5007043
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Funding
- National Science Foundation of China [21202167, 21272233]
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A new process for the ortho arylation of formanilides through palladium-catalyzed C-H activation is described. Formamide is reported as a transformable directing group in the transition-metal-catalyzed C-H functionalization reaction. The resulting biarylformanilide products can be readily transformed to the corresponding biarylisocyanides or N-heterocycles.
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