Journal
JOURNAL OF ORGANIC CHEMISTRY
Volume 79, Issue 1, Pages 106-116Publisher
AMER CHEMICAL SOC
DOI: 10.1021/jo4023342
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Funding
- CSIR, New Delhi [CSC-108]
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A novel and efficient method for the synthesis of diversely functionalized furans is developed via DBU-mediated tandem Michael addition/5-exo-dig-cycloisomerization of enynes and keto-methylenes. This [3 + 2]-annulation is operationally simple under metal-free reaction conditions with 100% atom economy and broad substrate scope.
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