Synthesis and Minisci Reactions of Organotrifluoroborato Building Blocks

Copper-catalyzed borylation of a variety of organic halides with bis(pinacolato)diboron allows the preparation of diverse potassium oigantrifluoroborates. The reactions are mild and general, providing access to a variety of interesting, boron-containing: building blocks, including those containing, piperidine, pyrrole, azetidine, tetrahydropyran, and oxetane substructures. Representation Minisci reactions are reported for select examples.