Journal
JOURNAL OF ORGANIC CHEMISTRY
Volume 78, Issue 11, Pages 5751-5755Publisher
AMER CHEMICAL SOC
DOI: 10.1021/jo400578m
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Funding
- Miami University
- NSF [CHE-1056420]
- Division Of Chemistry
- Direct For Mathematical & Physical Scien [1056420] Funding Source: National Science Foundation
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A Sc(OTf)(3)-catalyzed three-component cyclization reaction of arylamines, beta,gamma-unsaturated alpha-ketoesters and 1,3-dicarbonyl compounds was developed to synthesize highly substituted 1,4-dihydropyridines and fused bicyclic tetrahydropyridines carrying a quaternary all-carbon center.
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