Journal
JOURNAL OF ORGANIC CHEMISTRY
Volume 78, Issue 3, Pages 1242-1248Publisher
AMER CHEMICAL SOC
DOI: 10.1021/jo302471z
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Funding
- Fundamental Research Funds for the Central Universities [DL12DB03]
- China Postdoctoral Science Foundation [20110491013, 2012T50319]
- Heilongjiang Postdoctoral Grant [LBH-Z11251]
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An efficient one-pot route for the synthesis of benzo[4,5]imidazo[2,1-a] isoquinolines has been developed via nucleophilic addition of 2-aryl benzimidazoles to alkynyl bromides and subsequent palladium-catalyzed intramolecular C-H vinylation.
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