Journal
JOURNAL OF ORGANIC CHEMISTRY
Volume 78, Issue 8, Pages 4190-4195Publisher
AMER CHEMICAL SOC
DOI: 10.1021/jo400390t
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Funding
- Danish Agency for Science, Technology and Innovation
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A safe, practical, and scalable continuous flow protocol for the in situ generation of dimethylamine from DMF followed by nucleophilic aromatic substitution of a broad range of aromatic and heteroaromatic halides is reported.
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