Journal
JOURNAL OF ORGANIC CHEMISTRY
Volume 78, Issue 11, Pages 5705-5710Publisher
AMER CHEMICAL SOC
DOI: 10.1021/jo4003773
Keywords
-
Categories
Funding
- Ontario Ministry of Research and Innovation
Ask authors/readers for more resources
The reaction of 3-halo-4-aminopyridines with acyl chlorides and triethylamine is described. The pyridin-4-y1 alpha-substituted acetamide products were obtained in moderate to high yields. The presented rearrangement reaction, in which the presumed N-acylated intermediate reacts intramolecularly via nucleophilic aromatic substitution, results in a formal two-carbon insertion.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available