Journal
JOURNAL OF ORGANIC CHEMISTRY
Volume 78, Issue 11, Pages 5254-5263Publisher
AMER CHEMICAL SOC
DOI: 10.1021/jo400344m
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Funding
- Spanish Ministerio de Economia y Competitividad (MINECO) [CTQ2011-22589]
- Regional Government of Aragon [E-97]
- CSIC
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Isoquinolines, benzoisoquinolines, thieno[3,2-c]pyridines and fused heteroaryl[2,3-c] pyridines, with a wide variety of substituents at different positions of the aromatic or heteroaromatic rings, have been synthesized by Ru-catalyzed oxidative coupling of a broad range of benzylamines or heterocycles with internal alkynes. All benzylamines and heterocycles have unprotected primary amines as efficient directing groups.
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