Journal
JOURNAL OF ORGANIC CHEMISTRY
Volume 78, Issue 18, Pages 9457-9463Publisher
AMER CHEMICAL SOC
DOI: 10.1021/jo401109w
Keywords
-
Categories
Funding
- ChemBiotech (Munster, Germany)
Ask authors/readers for more resources
6-Substituted pyrrolo-dC-pyrrolo-dC mismatches selectively capture silver ions to form extraordinarily stable metal-mediated base pairs. One single modification in a 12-mer duplex causes a T-m increase of 36.0 degrees C relative to the metal-free mismatched duplex. Spectrophotometric titrations as well as ESI mass spectra confirmed the binding of two silver ions per base pair. The Ag+-mediated base pairs may permit the construction of metal-responsive DNA with a very high silver loading.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
