4.7 Article

Palladium(II)-Catalyzed Enantioselective Arylation of α-Imino Esters

Journal

JOURNAL OF ORGANIC CHEMISTRY
Volume 77, Issue 19, Pages 8541-8548

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/jo301423e

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Funding

  1. Ministry of Education [NCET-10-0371]
  2. NSFC [21072063]
  3. RFDP [20100172120020]
  4. Guangdong Natural Science Foundation [10351064101000000]

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A protocol for Pd(II)-catalyzed asymmetric arylation of N-aryl imino esters has been developed. The method affords a practical and direct access to chiral arylglycine derivatives in good yields and with high enantioselectivities.

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