Journal
JOURNAL OF ORGANIC CHEMISTRY
Volume 77, Issue 20, Pages 9148-9155Publisher
AMER CHEMICAL SOC
DOI: 10.1021/jo301705t
Keywords
-
Categories
Funding
- National Natural Science Foundation of China [21021001, 20902060]
- Ministry of Education [20110181130014]
- National Basic Research Program of China (973 Program) [2010CB833300]
Ask authors/readers for more resources
The catalytic enantioselective fluorination of N-H-free 3-substituted oxindoles was accomplished by a Sc(III)/N,N'-dioxide complex. Under mild reaction conditions, a series of 3-aryl- and 3-alkyl-3-fluoro-2-oxindoles were obtained in excellent yields (up to 98%) and enantioselectivities (up to 99% ee) by using N-fluorobisbenzenesulfonimide (NFSI) as the fluorination agent. MaxiPost was synthesized efficiently in 81% yield with 96% ee.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available