Journal
JOURNAL OF ORGANIC CHEMISTRY
Volume 77, Issue 21, Pages 9504-9509Publisher
AMER CHEMICAL SOC
DOI: 10.1021/jo301964m
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Funding
- National Natural Science Foundation of China [91021004]
- National Basic Research Program of China [2011CB921402]
- Department of Education, Anhui Province, China [KJ2010ZD0S]
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A palladium-catalyzed ortho-alkoxylation of anilides with both primary and secondary alcohols via ligand-directed C H activation has been explored. This alkoxylation promoted by catalytic methanesulfonic acid proceeds well at room temperature in most cases and affords aryl alkyl ethers in moderate to good yields.
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