Journal
JOURNAL OF ORGANIC CHEMISTRY
Volume 77, Issue 4, Pages 2053-2057Publisher
AMER CHEMICAL SOC
DOI: 10.1021/jo202577m
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Funding
- National Natural Science Foundation of China (NSFC) [21176039, 20876021, 20923006]
- Education Department of Liaoning Province [2009S021]
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An efficient protocol for the direct synthesis of 4-arylcoumarins via palladium-catalyzed oxidative Heck coupling reaction of coumarins and arylboronic acids was developed. 4-Arylcoumarins were obtained in moderate to excellent yields, and the reaction also showed tolerance toward functional groups such as hydro, methoxy, diethylamino, nitro, and chloro groups.
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