Journal
JOURNAL OF ORGANIC CHEMISTRY
Volume 77, Issue 9, Pages 4473-4478Publisher
AMER CHEMICAL SOC
DOI: 10.1021/jo300528b
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Funding
- Chinese Scholarship Council
- CNRS
- Rennes Metropole
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Ligand-free Pd(OAc)(2) was found to catalyze very efficiently the direct arylation of imidazo[1,2-a]pyridines at C3 under very low catalyst concentration. The reaction can be performed employing as little as 0.1-0.01 mol % catalyst with electron-deficient and some electron-excessive aryl bromides.
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