4.7 Article

Copper(II)-Catalyzed Dehydrogenative Cross-Coupling between Two Azoles

Journal

JOURNAL OF ORGANIC CHEMISTRY
Volume 77, Issue 17, Pages 7677-7683

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/jo301128y

Keywords

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Funding

  1. National NSF of China [21172155, 20972102, 21025205, 21021001, J1103315/J0104]
  2. National Basic Research Program of China (973 Program) [2011CB8086600]

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The copper(II)-catalyzed dehydrogenative coupling between two different azoles for the preparation of unsymmetrical biazoles has been developed. The current catalytic system can effectively control the chemoselectivity for heterocoupling over homocoupling.

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