4.7 Article

Palladium(0)-Catalyzed Allylic Alkylation of Diketoester-Dioxinones with Allyl Acetates under Neutral Conditions: Synthesis of Hexasubstituted Benzene Derivatives

Journal

JOURNAL OF ORGANIC CHEMISTRY
Volume 77, Issue 7, Pages 3524-3530

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/jo300340c

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Funding

  1. European Research Council (ERC)
  2. Swiss National Science Foundation (SNF)

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Intermolecular palladium(0)-catalyzed allylic alkylation of diketoester-dioxinones was performed under neutral conditions with 2-alkenyl and 2-cycloalkenyl acetates. Subsequent aromatization using cesium carbonate gave rise to isopropylidene-protected hexasubstituted resorcylates.

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