Journal
JOURNAL OF ORGANIC CHEMISTRY
Volume 78, Issue 2, Pages 702-705Publisher
AMER CHEMICAL SOC
DOI: 10.1021/jo301698v
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Funding
- Iowa State VPR office
- IPRT
- Petroleum Research Fund
- Division Of Chemistry
- Direct For Mathematical & Physical Scien [1040098] Funding Source: National Science Foundation
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We report that aryl phthalate esters are robust self-immolative linkers. This linker is easy to conjugate and releases output phenols upon cleaving a fluoride-sensitive mask to yield a benign phthalic acid byproduct, making these linkers potentially useful as fluoride sensors and promising for use in biological and materials applications.
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