Journal
JOURNAL OF ORGANIC CHEMISTRY
Volume 76, Issue 2, Pages 471-483Publisher
AMER CHEMICAL SOC
DOI: 10.1021/jo1018969
Keywords
-
Categories
Funding
- Welch Foundation [E-1571]
- NIGMS [R01GM077635]
- A. P. Sloan Foundation
- Camille and Henry Dreyfus Foundation
Ask authors/readers for more resources
The palladium-catalyzed direct arylation of indoles, pyrroles, and furans by aryl chlorides has been demonstrated. The method employs a palladium acetate catalyst, 2-(dicyclohexylphosphino)-biphenyl ligand, and an inorganic base. Electron-rich and electron-poor aryl chlorides as well as chloropyridine coupling partners can be used, and arylated heterocycles are obtained in moderate to good yields. Optimization of base, ligand, and solvent is required for achieving best results.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available