Journal
JOURNAL OF ORGANIC CHEMISTRY
Volume 76, Issue 9, Pages 3539-3544Publisher
AMER CHEMICAL SOC
DOI: 10.1021/jo2000012
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Funding
- Department of Chemistry, Jadavpur University
- CSIR, New Delhi, India
- UGC, Jadavpur University, New Delhi, India
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An iron-catalyzed intramolecular alkyne-aldehyde metathesis strategy of the alkynyl ether of salicylaldehyde derivatives has been developed which works under mild reaction conditions to produce the functionalized 2H-chromene derivatives. This protocol is compatible toward a wide range of functional groups, such as methoxy, fluoro, chloro, brow, and phenyl groups. This method provides an atom-economical and environmentally friendly approach for the synthesis of a series of substituted 2H-chromenes.
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