4.7 Article

A Method for the Deprotection of Alkylpinacolyl Boronate Esters

Journal

JOURNAL OF ORGANIC CHEMISTRY
Volume 76, Issue 9, Pages 3571-3575

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/jo200250y

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Funding

  1. Department of Chemistry at Virginia Tech
  2. National Institutes of Health [RO1 GM093834]

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A two-step procedure for deprotection of alkylpinacolyl boronate esters via transesterification with diethanolamine followed by hydrolysis was successfully developed with the advantages of tolerance to various functional groups, short reaction time, and ease of product isolation.

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