Journal
JOURNAL OF ORGANIC CHEMISTRY
Volume 76, Issue 19, Pages 8138-8142Publisher
AMER CHEMICAL SOC
DOI: 10.1021/jo201516v
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- Christian Doppler Research Foundation (CDG)
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A versatile and rapid microwave-assisted procedure for the palladium-catalyzed direct arylation of heterocycles by aryl bromides and heteroaryl bromides is described. This novel protocol features short coupling times (10-60 min) and low catalyst loadings (1 mol %) and allows the successful arylation of previously unreactive heterocyclic substrates.
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