4.7 Article

Three Rhodamine-Based Off-On Chemosensors with High Selectivity and Sensitivity for Fe3+ Imaging in Living Cells

Journal

JOURNAL OF ORGANIC CHEMISTRY
Volume 77, Issue 2, Pages 1143-1147

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/jo202056t

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Funding

  1. National Natural Science Foundation of China [20972124]
  2. China Postdoctoral Science Foundation [20080441180]
  3. Chinese National Science Foundation for Talent Training [J0830417]
  4. Chinese National Innovation Experiment Program for University Students [101069702]

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Three new rhodamine-based probes Y1-Y3 were synthesized as off-on chemosensors for Fe3+ imaging in living cells. The recognizing behaviors were investigated both experimentally and computationally. The crystal structure of the complex Y3-Fe3+ revealed that Fe3+ preferred to coordinate with the N atom of benzothiazole moiety rather than the O atom of carboxyl group.

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