4.7 Article

Cycloisomerization of Bifunctionalized Allenes: Synthesis of 3(2H)-Furanones in Water

Journal

JOURNAL OF ORGANIC CHEMISTRY
Volume 76, Issue 6, Pages 1934-1936

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/jo102416e

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Funding

  1. Dortmund University of Technology

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A simple protocol for the efficient synthesis of 3(2H)-furanones by cycloisomerization of allenic hydroxyketones is described. This transformation is achieved in water and in the absence of any expensive metal catalysts.

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