4.7 Article

Faulknerynes A-C from a Bahamian Sponge Diplastrella sp.: Stereoassignment by Critical Application of Two Exciton Coupled CD Methods

Journal

JOURNAL OF ORGANIC CHEMISTRY
Volume 76, Issue 3, Pages 894-901

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/jo102188q

Keywords

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Funding

  1. NSF (CRIF) [CHE0741968]
  2. NIH [CA122256, AI039987]
  3. Ruth L. Kirschstein National Research Service Award NIH/NCI [T32 CA009523]
  4. Division Of Chemistry
  5. Direct For Mathematical & Physical Scien [0741968] Funding Source: National Science Foundation

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Long-chain polyacetylene alcohols, faulknerynes A-C, along with known compounds diplynes A, C and E, were isolated from two specimens of the encrusting sponge, Diplastrella sp., collected from the surface of coral in the Bahamas. Two CD methods were critically evaluated for their suitability to terminal propargylic glycols and applied to assignment of configurations of faulkneryne A and diplyne C.

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