4.7 Article

Diastereoselective Tin-Free Tandem Radical Additions to 3-Formylchromones

Journal

JOURNAL OF ORGANIC CHEMISTRY
Volume 76, Issue 19, Pages 8076-8081

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/jo201350w

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Funding

  1. American Chemical Society [ACS PRF 49489-UNI]

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A tin-free tandem radical addition methodology onto 3-formylchromones is presented. This radical process yields functionalized chromone structures via two carbon carbon bond-forming steps. These products contain up to three contiguous stereocenters with good to excellent dr's and yields.

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