Journal
JOURNAL OF ORGANIC CHEMISTRY
Volume 76, Issue 10, Pages 3960-3967Publisher
AMER CHEMICAL SOC
DOI: 10.1021/jo200303c
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The total synthesis of atroviridin has been accomplished by a linear route involving the N-heterocyclic carbene (NHC)-catalyzed aroylation of the fluorobenzene derivative, Claisen cyclization of the O-propargylated benzo-phenones, and intramolecular 1,4-addition of the quinone intermediates. The result provides a viable route to xanthone natural products.
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