4.7 Article

Aliphatic C-H to C-C Conversion: Synthesis of (-)-Cameroonan-7α-ol

Journal

JOURNAL OF ORGANIC CHEMISTRY
Volume 76, Issue 6, Pages 1874-1882

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/jo200075v

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Funding

  1. NSF [0541775, CHE 0840401]
  2. NIH [GM42056]
  3. Division Of Chemistry
  4. Direct For Mathematical & Physical Scien [0840401, 0541775] Funding Source: National Science Foundation

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In the course of a synthesis of the tricyclic sesquiterpene (-)-cameroonan-7 alpha-ol from the acyclic (+)-citronellal, seven aliphatic C-H bonds were converted to C-C bonds, and three rings and four new stereogenic centers were established.

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