Journal
JOURNAL OF ORGANIC CHEMISTRY
Volume 75, Issue 14, Pages 4657-4673Publisher
AMER CHEMICAL SOC
DOI: 10.1021/jo1006812
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Funding
- Scripps Research Institute
- Skaggs Institute for Chemical Biology
- NIH
- NSF
- Alfred P. Sloan Foundation
- Austrian Science Foundation (FWF) [J2899]
- Amgen
- Bristol-Myers Squibb
- Pfizer
- Roche
- GlaxoSmithKline
- Astra Zeneca
- Dupont
- Searle Foundation
- Beckmann Foundation
- Austrian Science Fund (FWF) [J2899] Funding Source: Austrian Science Fund (FWF)
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The field of total synthesis has a rich history and a vibrant future. Landmark advances and revolutionary strides in the logic of synthesis have put the practicing chemist in the enviable position of being able to create nearly any molecule with enough time and effort. The stage is now set for organic chemists to aim for ideality in the way molecules are synthesized. This perspective presents a simple and informative definition of ideality and demonstrates its use during the self-evaluation of several syntheses from our laboratory.
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