4.7 Article

Enantioselective Henry Reaction Catalyzed by CuII Salt and Bipiperidine

Journal

JOURNAL OF ORGANIC CHEMISTRY
Volume 75, Issue 4, Pages 1313-1316

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/jo902664v

Keywords

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Funding

  1. Estonian Science Foundation [6662]
  2. Ministry of Education and Research [0142725s06]
  3. EU European Regional Development Fund [3.2.0101.08-0017]

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A complex derived from the enantiomeric bipiperidine and copper(II) acetate hydrate is an efficient catalyst for the enantioselective Henry reaction. The easy availability of both catalyst components, mild reaction conditions, high yield, and good to excellent enantioselectivity make the catalyst useful for everyday practice.

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