4.7 Article

Copper-Mediated Cyclization-Halogenation and Cyclization-Cyanation Reactions of β-Hydroxyalkynes and o-Alkynylphenols and Anilines

Journal

JOURNAL OF ORGANIC CHEMISTRY
Volume 75, Issue 10, Pages 3412-3419

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/jo1005119

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Funding

  1. Australian Research Council
  2. University of Wollongong

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The CuX (X = I, Br, Cl, CN)-mediated cyclization-halogenation and cyclization-cyanation reactions of beta-hydroxyalkynes and o-alkynylphenol and -aniline derivatives give rise to 3-halo- and 3-cyanofuro[3,2-b]pyrroles, 3-iodo-, 3-bromo-, and 3-cyanobenzofurans, and 3-cyanoindoles, respectively.

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