4.7 Article

Gold(III)-Catalyzed Tandem Reaction of O-Arylhydroxylamines with 1,3-Dicarbonyl Compounds: Highly Selective Synthesis of 3-Carbonylated Benzofuran Derivatives

Journal

JOURNAL OF ORGANIC CHEMISTRY
Volume 75, Issue 18, Pages 6300-6303

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/jo101357d

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Funding

  1. Natural Science Foundation of Zhejiang Province [Y407168]
  2. Foundation of Education of Zhejiang Province [Z200803599]
  3. Opening Foundation of Zhejiang Provincial Top Key Discipline

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A highly regioselective protocol for the synthesis of 3-carbonylated benzofuran derivatives has been developed involving the gold(III)-catalyzed tandem condensation/rearrangement/cyclization reaction of O-arylhydroxylamines with 1,3-dicarbonyl compounds.

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