4.7 Article

Substrate-Controlled and Organocatalytic Asymmetric Synthesis of Carbocyclic Amino Acid Dipeptide Mimetics

Journal

JOURNAL OF ORGANIC CHEMISTRY
Volume 75, Issue 9, Pages 2861-2876

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/jo100017t

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Funding

  1. NSERC
  2. Novartis (Basel, Switzerland)

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The asymmetric synthesis of a carbocyclic delta-amino acid representing the P-2/P-3 subunit of a nonpeptidic truncated peptidomimetic molecule is described relying on two independent approaches.

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