4.7 Article

Polyfluorination Using IF5

Journal

JOURNAL OF ORGANIC CHEMISTRY
Volume 75, Issue 21, Pages 7393-7399

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/jo101672g

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The polyfluorination of alpha-(arylthio)carbonyl compounds was achieved by a successive application of polyfluorination using IF5, Friedel Crafts arylation, and desulfurizing fluorination using IF5. Three to six fluorine atoms were selectively introduced to the carbons located between the aromatic ring and the carbonyl group.

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