Journal
JOURNAL OF ORGANIC CHEMISTRY
Volume 75, Issue 10, Pages 3274-3282Publisher
AMER CHEMICAL SOC
DOI: 10.1021/jo100228u
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Funding
- National Natural Science Foundation of China [20721003, 20872153]
- International Collaboration Projects [20720102040]
- 863 Hi-Tech Program of China [2006AA020602, 2006AA10A201]
- National S&T Major Projects [2009ZX09301-001, 2009ZX09501-001, 2009ZX09501-010]
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We have developed a simple method for the synthesis of pyrrolo/pyrido[2,1-a][1,3]benzoxazinones and pyrrolo/pyrido[2,1-a]quinazolinones from 2-amino benzoic acids and 2-amino benzamides via a gold(I)-catalyzed tandem coupling/cyclization process. The tricyclic or polycyclic molecular architectures were constructed in one pot with the formation of three new bonds.
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