4.7 Article

Palladium-Catalyzed Direct Oxidative Alkenylation of Azoles

Journal

JOURNAL OF ORGANIC CHEMISTRY
Volume 75, Issue 15, Pages 5421-5424

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/jo101214y

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Funding

  1. MEXT
  2. JSPS

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The direct heteroaromatic sp(2) C-H alkenylation of 2-substituted azole compounds with alkenes proceeds in the presence of Pd(OAc)(2) and AgOAc as catalyst and oxidant, respectively, to afford the corresponding 5-alkenylated azoles in good yields.

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