Journal
JOURNAL OF ORGANIC CHEMISTRY
Volume 75, Issue 6, Pages 2073-2076Publisher
AMER CHEMICAL SOC
DOI: 10.1021/jo902519j
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- MICINN [CTQ2007-61126]
- Spanish Ministerio de Ciencia c Innovacion (MICINN)
- European Social fond
- MICINN
- EU [FP7]
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Baeyer-Villiger monooxygenases have been tested in the oxidation of racemic benzofused ketones. When employing a single Mutant of phenylacetone monooxygenase (M446G PAMO) under the proper reaction conditions, it was possible to achieve 3-substituted 3,4-dihydroisocoumarins with high yields and optical purities through regioselective dynamic kinetic resolution Processes.
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