4.7 Article

A Concise Access to 3-Substituted 2-Pyrones

Journal

JOURNAL OF ORGANIC CHEMISTRY
Volume 75, Issue 22, Pages 7962-7965

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/jo101843a

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Funding

  1. Deutsche Forschungsgemeinschaft (DFG) [MA4861/3-1]
  2. Max-Planck Society
  3. Max-Planck-Institut fur Kohlenforschung

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The development of a modular synthesis of 3-substituted-2-pyrones is described The attainment of this strategy hinges on a new electrophilic pyrone derivative which can be readily prepared on a multigram scale and which performs very competently in metal-catalyzed cross-coupling reactions with a variety of nucleophiles

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